This set capitalizes on Persian's few advantages over Ambipom, specifically his higher Special Attack and access to Hypnosis, as well as his equally high Speed stat, in order to make him a rather effective sweeper. Although Persian's initial Special Attack is still pretty bad, it becomes surprisingly decent after a Nasty Plot; when further boosted by Life Orb, it is at least enough to dispose of many switch-ins that expect a typical physical set, such as Rhyperior and Donphan. Hypnosis can allow Persian a free setup opportunity he would otherwise not have had, which is especially potent if he manages to hit a would-be counter as well. Swift is Persian's strongest special STAB attack after Technician, and it will be his primary attacking option. Water Pulse is boosted likewise, and it achieves perfect coverage in UU (besides Shedinja) alongside Swift.
Substitute can be a viable alternative to Hypnosis, and it can be really helpful in easing prediction and blocking status. However, losing the ability to instantly suspend an opponent in sleep is rather disappointing. Taunt is also an option that can allow Persian to grab a few extra Nasty Plot boosts against Chansey or stop opposing setup sweepers from doing their thing. Icy Wind and Thunderbolt can be used in the second and fourth slots, respectively, if you decide against both Hypnosis and Substitute, for impressive coverage. Finally, Dark Pulse and Shadow Ball are options to hit Ghost-types, most notably Mismagius and Rotom, harder.
Dual screen support is very helpful to Persian, as he is incredibly frail. Pokemon such as Uxie and Mesprit make great candidates to set them up, as they have impressive bulk and a resistance to Fighting. Both also sport the ability to use Stealth Rock, a most valuable asset to any sweeper. Further Spikes and Toxic Spikes support will also be appreciated, and both can be provided by a Pokemon like Qwilfish. Finally, even after several Nasty Plot boosts, Persian just does not have the power needed to break through the infamous Chansey, and to a lesser extent, Registeel. Milotic can also prove troublesome if Persian is without Thunderbolt. In return, these Pokemon can easily smash him with their own attacks, or cripple him with status. A Pokemon such as Toxicroak can be very useful in dealing with these Pokemon, as it is able to use its Fighting STAB to easily dispose of Chansey and Registeel, or scare them off and set up. Its ability, Dry Skin, also allows it to switch into Milotic with near impunity.